Recent Articles

List of articles

Screening, Synthesis, and Characterization of a More Rapidly Dissolving Celecoxib Crystal Form

ACS Omega
2024-07-09 | journal-article
DOI: 10.1021/acsomega.4c03188 
 


Contribution of a C-Terminal Extension to the Substrate Affinity and Oligomeric Stability of Aldehyde Dehydrogenase from Thermus thermophilus HB27

Biochemistry
2024-05-07 | journal-article
DOI: 10.1021/acs.biochem.3c00698 
 


Continuous Microfluidic Antisolvent Crystallization as a Bottom-Up Solution for the Development of Long-Acting Injectable Formulations

Pharmaceutics
2024-03-08 | journal-article
DOI: 10.3390/pharmaceutics16030376 
 


Development of long-acting injectable suspensions by continuous antisolvent crystallization: An integrated bottom-up processInternational

International Journal of Pharmaceutics
2023-12 | journal-article
DOI: 10.1016/j.ijpharm.2023.123550 
 


Structural modifications for the conversion of proteins and peptides into stable dried powder formulations: A review

Journal of Drug Delivery Science and Technology
2023-11 | journal-article
DOI: 10.1016/j.jddst.2023.104992 
 


A comparative study of dry and wet top-down milling approaches for the preparation of microparticle suspensions

Powder Technology
2023-10 | journal-article
DOI: 10.1016/j.powtec.2023.118829 
Part of ISSN: 0032-5910 
 


Investigating the effectiveness of the main channel in microfluidic liquid-liquid extraction processInternational

Communications in Heat and Mass Transfer
2023-10 | journal-article
DOI: 10.1016/j.icheatmasstransfer.2023.106986 
Part of ISSN: 0735-1933 
 


Sorbitol-coated indomethacin and naproxen particles produced by supercritical CO2-assisted spray drying

The Journal of Supercritical Fluids
2023-08 | journal-article
DOI: 10.1016/j.supflu.2023.105969 
Part of ISSN: 0896-8446 
 


Amorphization versus cocrystallization of celecoxib-tramadol hydrochloride using CO2-assisted nano-spray drying

Journal of CO2 Utilization
2023-07 | journal-article
DOI: 10.1016/j.jcou.2023.102529 
 


Nucleation kinetics-based solvent selection for the liquid antisolvent crystallization of a lipophilic intermediate

Journal of Molecular Liquids
2023 | journal-article
DOI: 10.1016/j.molliq.2023.121306 
EID: 2-s2.0-85147456602
Part of ISSN: 01677322 
 


Production of hydrochlorothiazide nanoparticles with increased permeability using top-spray coating process

Journal of Supercritical Fluids
2023 | journal-article
DOI: 10.1016/j.supflu.2022.105788 
EID: 2-s2.0-85141989849
Part of ISSN: 08968446 
 


Controlling the Polymorphism of Indomethacin with Poloxamer 407 in a Gas Antisolvent Crystallization Process

ACS Omega
2022-12-06 | journal-article
DOI: 10.1021/acsomega.2c05259 
 


Production of biopharmaceutical dried-powders using supercritical CO2 technology

The Journal of Supercritical Fluids
2022-08 | journal-article
DOI: 10.1016/j.supflu.2022.105645 
Part of ISSN: 0896-8446 
 


Solid-state and particle size control of pharmaceutical cocrystals using atomization-based techniques

International Journal of Pharmaceutics
2022-06 | journal-article
DOI: 10.1016/j.ijpharm.2022.121798 
Part of ISSN: 0378-5173 
 


Thermodynamic solubility of celecoxib in organic solvents

CrystEngComm
2022 | journal-article
DOI: 10.1039/d1ce01415c 
Part of ISSN: 1466-8033 
 


Generation and Physicochemical Characterization of Posaconazole Cocrystals using Gas Antisolvent (GAS) and Supercritical Solvent (CSS) Methods

The Journal of Supercritical Fluids
2021-04 | journal-article
DOI: 10.1016/j.supflu.2020.105134 
Part of ISSN: 0896-8446 
 


Pharmaceutical nanoparticle isolation using CO2-assisted dynamic bed coating

International Journal of Pharmaceutics
2021-01-05 | journal-article
DOI: 10.1016/j.ijpharm.2020.120032 
Part of ISSN: 0378-5173 
 


Production and isolation of pharmaceutical drug nanoparticles

International Journal of Pharmaceutics
2021 | journal-article
DOI: 10.1016/j.ijpharm.2021.120708 
EID: 2-s2.0-85107049291
Part of ISSN: 18733476 03785173 
 


Cortisone and cortisol break hydrogen-bonding rules to make a drug–prodrug solid solution

IUCrJ
2020-11-01 | journal-article
DOI: 10.1107/S2052252520013263 
 


Investigating Process Variables and Additive Selection To Optimize Polymorphic Control of Carbamazepine in a CO2 Antisolvent Crystallization Process

Organic Process Research & Development
2020-06-19 | journal-article
DOI: 10.1021/acs.oprd.9b00545 
 

A rational approach towards spray drying of biopharmaceuticals: The case of lysozyme

Powder Technology
2020-04 | journal-article
DOI: 10.1016/j.powtec.2020.02.057 
Part of ISSN: 0032-5910 
 


Development and validation of a two-dimensional population balance model for a supercritical CO<inf>2</inf> antisolvent batch crystallization process

Advanced Powder Technology
2020 | journal-article
DOI: 10.1016/j.apt.2020.06.008 
EID: 2-s2.0-85088112436
Part of ISBN: 15685527 09218831
 


Solubility and thermodynamic analysis of ketoprofen in organic solvents

International Journal of Pharmaceutics
2020 | journal-article
DOI: 10.1016/j.ijpharm.2020.119686 
EID: 2-s2.0-85089106599
Part of ISBN: 18733476 03785173
 


Amorphous Solid Dispersion of Ibuprofen: A Comparative Study on the Effect of Solution Based Techniques

International Journal of Pharmaceutics
2019-10 | journal-article
DOI: 10.1016/j.ijpharm.2019.118816 
 


Controlling Polymorphism of Carbamazepine Nanoparticles in a Continuous Supercritical-CO2-Assisted Spray Drying Process

Crystal Growth & Design
2019-07-03 | journal-article
DOI: 10.1021/acs.cgd.9b00154 
 


Unraveling the Link between Solvent-Mediated Proton Transfer and the Salt Formation of Saccharin and Sulfamethazine

Crystal Growth & Design
2019-02-06 | journal-article
DOI: 10.1021/acs.cgd.8b01015 
 


Co-crystal polymorphic control by nanodroplet and electrical confinement

CrystEngComm
2019 | journal-article
DOI: 10.1039/C9CE00060G 
 


From batch to continuous — New opportunities for supercritical CO2 technology in pharmaceutical manufacturing

European Journal of Pharmaceutical Sciences
2019 | journal-article
DOI: 10.1016/j.ejps.2019.104971 
EID: 2-s2.0-85068640740
 


Spray drying of pharmaceuticals and biopharmaceuticals: Critical parameters and experimental process optimization approaches

European Journal of Pharmaceutical Sciences
2019 | journal-article
DOI: 10.1016/j.ejps.2018.10.026 
EID: 2-s2.0-85056659367
 


Creating Cocrystals: A Review of Pharmaceutical Cocrystal Preparation Routes and Applications

Crystal Growth & Design
2018-10-03 | journal-article
DOI: 10.1021/acs.cgd.8b00933 
 


Supercritical carbon dioxide-based technologies for the production of drug nanoparticles/nanocrystals – A comprehensive review

Advanced Drug Delivery Reviews
2018 | journal-article
DOI: 10.1016/j.addr.2018.07.010 
EID: 2-s2.0-85050336466
 


Insight into the Role of Additives in Controlling Polymorphic Outcome: A CO2-Antisolvent Crystallization Process of Carbamazepine

Crystal Growth & Design
2017-09-06 | journal-article
DOI: 10.1021/acs.cgd.7b00163 
 


Spray drying ternary amorphous solid dispersions of ibuprofen – An investigation into critical formulation and processing parameters

European Journal of Pharmaceutics and Biopharmaceutics
2017 | journal-article
DOI: 10.1016/j.ejpb.2017.08.005 
EID: 2-s2.0-85027894709
 


Synthesis and particle engineering of cocrystals
2015-03-19 | patent
 


Insight into the Mechanisms of Cocrystallization of Pharmaceuticals in Supercritical Solvents

Crystal Growth and Design
2015 | journal-article
DOI: 10.1021/acs.cgd.5b00200 
EID: 2-s2.0-84934780060
 


New thermoresistant polymorph from CO2 recrystallization of minocycline hydrochloride

Pharmaceutical Research
2014 | journal-article
DOI: 10.1007/s11095-014-1406-3 
EID: 2-s2.0-84932097751
 


Tuning physicochemical properties of theophylline by cocrystallization using the supercritical fluid enhanced atomization technique

Journal of Supercritical Fluids
2014 | journal-article
DOI: 10.1016/j.supflu.2013.12.011 
EID: 2-s2.0-84892183277
 


New crystalline minocycline chlorohydrate, useful for preparing composite materials, prostheses, bone cements, implants, and controlled drug delivery formulations for the treatment of bacterial infections
2013-06-27 | patent
 


Vaccine against strangles of equidae comprises composite particles of specific size that retain intrinsic adjuvanticity present in aqueous total extracts of Streptococcus equi
2013-03-01 | patent
 


Single-step co-crystallization and lipid dispersion by supercritical enhanced atomization

Crystal Growth and Design
2013 | journal-article
DOI: 10.1021/cg401131x 
EID: 2-s2.0-84887769901


Development of a novel mucosal vaccine against strangles by supercritical enhanced atomization spray-drying of Streptococcus equi extracts and evaluation in a mouse model

European Journal of Pharmaceutics and Biopharmaceutics
2012 | journal-article
DOI: 10.1016/j.ejpb.2012.07.005 
EID: 2-s2.0-84867877552
 


Powder X-ray diffraction method for the quantification of cocrystals in the crystallization mixture

Drug Development and Industrial Pharmacy
2012 | journal-article
DOI: 10.3109/03639045.2011.633263 
EID: 2-s2.0-84863432676
 


Theophylline polymorphs by atomization of supercritical antisolvent induced suspensions

Journal of Supercritical Fluids
2011 | journal-article
DOI: 10.1016/j.supflu.2011.05.012 
EID: 2-s2.0-80051470431
 


Antibacterial activity of tigecycline micro/nanoparticles under supercritical fluids conditions

European Cells and Materials
2010 | journal-article
EID: 2-s2.0-84860913505

 

Screening for pharmaceutical cocrystals using the supercritical fluid enhanced atomization process

Journal of Supercritical Fluids
2010 | journal-article
DOI: 10.1016/j.supflu.2010.01.010 
EID: 2-s2.0-77951258063


 
Anti-solvent effect in the production of lysozyme nanoparticles by supercritical fluid-assisted atomization processes

Journal of Supercritical Fluids
2009 | journal-article
DOI: 10.1016/j.supflu.2008.06.006 
EID: 2-s2.0-61349140587


 
Formation of indomethacin-saccharin cocrystals using supercritical fluid technology

European Journal of Pharmaceutical Sciences
2009 | journal-article
DOI: 10.1016/j.ejps.2009.05.010 
EID: 2-s2.0-67650220896